PK/PD Studies


We perform discovery in vivo pharmacokinetic studies in isolation and in combination with pharmacodynamics/ efficacy/ toxicity evaluations. The correlation of PK and functional read-outs helps elucidate the relationship between PK and PD, understand the mechanism of drug action, and identify PK properties for further improvement and optimal compound design.

Discovery in Vivo Pharmacokinetic Services:

  • Collection of Blood and Tissues from Test-Agent-Treated Mice and Rats for Bioanalysis
  • In vivo PK Screens
    • Clearance/ Half-Life/ Bioavailability
    • Target Organ Penetration
  • Pharmacology Support
    • Exposure in Efficacy Models
  • Toxicology Support
    • Exposure in Discovery Toxicology Studies
  • Bioanalytical Services

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